RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking
RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking
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Author / Creator
Lin, Xiaosi , Yang, Ting , Wang, Shicong , Wang, Zhen , Yun, Ye , Sun, Lixiang , Zhou, Yunhe , Xu, Xiaohui , Akazawa, Chihiro , Hong, Wanjin and Wang, Tuanlao
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The HOPS complex serves as a tethering complex with GEF activity for Ypt7p in yeast to regulate late endosomal membrane maturation. While the role of HOPS complex is well established in yeast cells, its functional and mechanistic aspects in mammalian cells are less well defined. In this study, we report that RILP, a downstream effector of Rab7, int...
Alternative Titles
Full title
RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4250914
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4250914
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep07282
