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Functional chromatin features are associated with structural mutations in cancer

Functional chromatin features are associated with structural mutations in cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4253614

Functional chromatin features are associated with structural mutations in cancer

About this item

Full title

Functional chromatin features are associated with structural mutations in cancer

Publisher

England: BioMed Central Ltd

Journal title

BMC genomics, 2014-11, Vol.15 (1), p.1013-1013, Article 1013

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Structural mutations (SMs) play a major role in cancer development. In some cancers, such as breast and ovarian, DNA double-strand breaks (DSBs) occur more frequently in transcribed regions, while in other cancer types such as prostate, there is a consistent depletion of breakpoints in transcribed regions. Despite such regularity, little is underst...

Alternative Titles

Full title

Functional chromatin features are associated with structural mutations in cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4253614

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4253614

Other Identifiers

ISSN

1471-2164

E-ISSN

1471-2164

DOI

10.1186/1471-2164-15-1013

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