Functional chromatin features are associated with structural mutations in cancer
Functional chromatin features are associated with structural mutations in cancer
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Structural mutations (SMs) play a major role in cancer development. In some cancers, such as breast and ovarian, DNA double-strand breaks (DSBs) occur more frequently in transcribed regions, while in other cancer types such as prostate, there is a consistent depletion of breakpoints in transcribed regions. Despite such regularity, little is underst...
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Full title
Functional chromatin features are associated with structural mutations in cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4253614
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4253614
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ISSN
1471-2164
E-ISSN
1471-2164
DOI
10.1186/1471-2164-15-1013