AURKA regulates JAK2–STAT3 activity in human gastric and esophageal cancers
AURKA regulates JAK2–STAT3 activity in human gastric and esophageal cancers
About this item
Full title
Author / Creator
Publisher
United States: Elsevier B.V
Journal title
Language
English
Formats
Publication information
Publisher
United States: Elsevier B.V
Subjects
More information
Scope and Contents
Contents
Aurora kinase A is a frequently amplified and overexpressed gene in upper gastrointestinal adenocarcinomas (UGCs). Using in vitro cell models of UGCs, we investigated whether AURKA can regulate Signal Transducer and Activator of Transcription 3 (STAT3). Our data indicate that overexpression of AURKA in FLO-1 and AGS cells increase STAT3 phosphoryla...
Alternative Titles
Full title
AURKA regulates JAK2–STAT3 activity in human gastric and esophageal cancers
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4254172
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4254172
Other Identifiers
ISSN
1574-7891
E-ISSN
1878-0261
DOI
10.1016/j.molonc.2014.05.012