Epithelial sodium channel abundance is decreased by an unfolded protein response induced by hyperosm...
Epithelial sodium channel abundance is decreased by an unfolded protein response induced by hyperosmolality
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Publisher
United States: John Wiley & Sons, Inc
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Language
English
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Publisher
United States: John Wiley & Sons, Inc
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Contents
Large shifts of osmolality occur in the kidney medulla as part of the urine concentrating mechanism. Hyperosmotic stress profoundly challenges cellular homeostasis and induces endoplasmic reticulum (ER) stress. Here, we examined the unfolded protein response (UPR) in hyperosmotically‐challenged principal cells of the kidney collecting duct (CD) and...
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Full title
Epithelial sodium channel abundance is decreased by an unfolded protein response induced by hyperosmolality
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4255800
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4255800
Other Identifiers
ISSN
2051-817X
E-ISSN
2051-817X
DOI
10.14814/phy2.12169