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Epithelial sodium channel abundance is decreased by an unfolded protein response induced by hyperosm...

Epithelial sodium channel abundance is decreased by an unfolded protein response induced by hyperosm...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4255800

Epithelial sodium channel abundance is decreased by an unfolded protein response induced by hyperosmolality

About this item

Full title

Epithelial sodium channel abundance is decreased by an unfolded protein response induced by hyperosmolality

Publisher

United States: John Wiley & Sons, Inc

Journal title

Physiological reports, 2014-11, Vol.2 (11), p.e12169-n/a

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Large shifts of osmolality occur in the kidney medulla as part of the urine concentrating mechanism. Hyperosmotic stress profoundly challenges cellular homeostasis and induces endoplasmic reticulum (ER) stress. Here, we examined the unfolded protein response (UPR) in hyperosmotically‐challenged principal cells of the kidney collecting duct (CD) and...

Alternative Titles

Full title

Epithelial sodium channel abundance is decreased by an unfolded protein response induced by hyperosmolality

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4255800

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4255800

Other Identifiers

ISSN

2051-817X

E-ISSN

2051-817X

DOI

10.14814/phy2.12169

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