X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors
X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
This study solved structures of the glutamate-gated chloride channel (GluCl), a Cys-loop receptor from
C. elegans
, in an
apo
, closed state and in a lipid-bound state — comparison of these structures with a previously published structure of GluCl in an ivermectin-bound state reveals what conformational changes probably occur as this me...
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Full title
X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4255919
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4255919
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13669
