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CCR1-mediated accumulation of myeloid cells in the liver microenvironment promoting mouse colon canc...

CCR1-mediated accumulation of myeloid cells in the liver microenvironment promoting mouse colon canc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4256518

CCR1-mediated accumulation of myeloid cells in the liver microenvironment promoting mouse colon cancer metastasis

About this item

Full title

CCR1-mediated accumulation of myeloid cells in the liver microenvironment promoting mouse colon cancer metastasis

Publisher

Dordrecht: Springer Netherlands

Journal title

Clinical & experimental metastasis, 2014-12, Vol.31 (8), p.977-989

Language

English

Formats

Publication information

Publisher

Dordrecht: Springer Netherlands

More information

Scope and Contents

Contents

To understand colon cancer metastasis, we earlier analyzed a mouse model that developed liver metastasis of cancer cells disseminated from the spleen. We suggested that CCR1
+
bone marrow (BM)-derived cells are recruited to the microenvironment of disseminated colon cancer cells, and produce metalloproteinases MMP9 and MMP2, helping metastati...

Alternative Titles

Full title

CCR1-mediated accumulation of myeloid cells in the liver microenvironment promoting mouse colon cancer metastasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4256518

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4256518

Other Identifiers

ISSN

0262-0898

E-ISSN

1573-7276

DOI

10.1007/s10585-014-9684-z

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