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SOX2 regulates self-renewal and tumorigenicity of stem-like cells of head and neck squamous cell car...

SOX2 regulates self-renewal and tumorigenicity of stem-like cells of head and neck squamous cell car...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4260038

SOX2 regulates self-renewal and tumorigenicity of stem-like cells of head and neck squamous cell carcinoma

About this item

Full title

SOX2 regulates self-renewal and tumorigenicity of stem-like cells of head and neck squamous cell carcinoma

Publisher

London: Nature Publishing Group UK

Journal title

British journal of cancer, 2014-11, Vol.111 (11), p.2122-2130

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Background:
Head and neck squamous cell carcinomas (HNSCCs) display cellular heterogeneity and contain cancer stem cells (CSCs). Sex-determining region Y [SRY]-box (SOX)2 is an important regulator of embryonic stem cell fate and is aberrantly expressed in several types of human tumours. Nonetheless, the role of SOX2 in HNSCC remains unclear.
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Alternative Titles

Full title

SOX2 regulates self-renewal and tumorigenicity of stem-like cells of head and neck squamous cell carcinoma

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4260038

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4260038

Other Identifiers

ISSN

0007-0920

E-ISSN

1532-1827

DOI

10.1038/bjc.2014.528

How to access this item