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Probucol suppresses human glioma cell proliferation in vitro via ROS production and LKB1-AMPK activa...

Probucol suppresses human glioma cell proliferation in vitro via ROS production and LKB1-AMPK activa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4261125

Probucol suppresses human glioma cell proliferation in vitro via ROS production and LKB1-AMPK activation

About this item

Full title

Probucol suppresses human glioma cell proliferation in vitro via ROS production and LKB1-AMPK activation

Publisher

London: Nature Publishing Group UK

Journal title

Acta pharmacologica Sinica, 2014-12, Vol.35 (12), p.1556-1565

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Aim: Probucol, an anti-hyperlipidemic drug, has been reported to exert antitumor activities at various stages of tumor initiation, promotion and progression. In this study we examined whether the drug affected glioma cell growth in vitro and the underlying mechanisms. Methods: Human glioma U87 and glioblastoma SF295 cell lines were used. Cell proli...

Alternative Titles

Full title

Probucol suppresses human glioma cell proliferation in vitro via ROS production and LKB1-AMPK activation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4261125

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4261125

Other Identifiers

ISSN

1671-4083

E-ISSN

1745-7254

DOI

10.1038/aps.2014.88

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