Neutrophils with myeloid derived suppressor function deplete arginine and constrain T cell function...
Neutrophils with myeloid derived suppressor function deplete arginine and constrain T cell function in septic shock patients
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Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Impaired T cell function in sepsis is associated with poor outcome, but the mechanisms are unclear. In cancer, arginase-expressing myeloid derived suppressor cells (MDSCs) deplete arginine, impair T cell receptor CD3 zeta-chain expression and T cell function and are linked to poor clinical outcome, but their role during acute human infectious disea...
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Full title
Neutrophils with myeloid derived suppressor function deplete arginine and constrain T cell function in septic shock patients
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4261583
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4261583
Other Identifiers
ISSN
1364-8535
E-ISSN
1466-609X,1364-8535
DOI
10.1186/cc14003
