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B-RafV600E inhibits sodium iodide symporter expression via regulation of DNA methyltransferase 1

B-RafV600E inhibits sodium iodide symporter expression via regulation of DNA methyltransferase 1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4261912

B-RafV600E inhibits sodium iodide symporter expression via regulation of DNA methyltransferase 1

About this item

Full title

B-RafV600E inhibits sodium iodide symporter expression via regulation of DNA methyltransferase 1

Publisher

London: Nature Publishing Group UK

Journal title

Experimental & molecular medicine, 2014-11, Vol.46 (11), p.e120-e120

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

B-RafV600E mutant is found in 40–70% of papillary thyroid carcinoma (PTC) and has an important role in the pathogenesis of PTC. The sodium iodide symporter (NIS) is an integral plasma membrane glycoprotein that mediates active iodide transport into the thyroid follicular cells, and B-RafV600E has been known to be associated with the loss of NIS exp...

Alternative Titles

Full title

B-RafV600E inhibits sodium iodide symporter expression via regulation of DNA methyltransferase 1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4261912

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4261912

Other Identifiers

ISSN

2092-6413,1226-3613

E-ISSN

2092-6413

DOI

10.1038/emm.2014.68

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