B-RafV600E inhibits sodium iodide symporter expression via regulation of DNA methyltransferase 1
B-RafV600E inhibits sodium iodide symporter expression via regulation of DNA methyltransferase 1
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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B-RafV600E mutant is found in 40–70% of papillary thyroid carcinoma (PTC) and has an important role in the pathogenesis of PTC. The sodium iodide symporter (NIS) is an integral plasma membrane glycoprotein that mediates active iodide transport into the thyroid follicular cells, and B-RafV600E has been known to be associated with the loss of NIS exp...
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B-RafV600E inhibits sodium iodide symporter expression via regulation of DNA methyltransferase 1
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4261912
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4261912
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ISSN
2092-6413,1226-3613
E-ISSN
2092-6413
DOI
10.1038/emm.2014.68