Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at codin...
Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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RNA polymerase II (RNAPII) pausing/termination shortly after initiation is a hallmark of gene regulation. Here, we show that negative elongation factor (NELF) interacts with Integrator complex subunits (INTScom), RNAPII and Spt5. The interaction between NELF and INTScom subunits is RNA and DNA independent. Using both human immunodeficiency virus ty...
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Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4263189
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4263189
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms6531
