Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed...
Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Aims/hypothesis
Amyloid deposition and inflammation are characteristic of islet pathology in type 2 diabetes. The aim of this study was to determine whether islet amyloid formation is required for the development of islet inflammation in vivo.
Methods
Human islet amyloid polypeptide transgenic mice and non-transgenic littermates (the latte...
Alternative Titles
Full title
Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4267509
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4267509
Other Identifiers
ISSN
0012-186X
E-ISSN
1432-0428
DOI
10.1007/s00125-014-3304-y