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A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer

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A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4270133

A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer

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Publisher

London: Nature Publishing Group UK

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Contents

The next generation of genetically engineered mouse models of pancreatic cancer involving a new inducible dual-recombinase system that combines Flp-
FRT
and Cre-
loxP
.
Genetically engineered mouse models (GEMMs) have dramatically improved our understanding of tumor evolution and therapeutic resistance. However, sequential genetic ma...

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Full title

A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer

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Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4270133

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4270133

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.3646

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