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Correlating EGFR Expression with Receptor-Binding Properties and Internalization of 64Cu-DOTA-Cetuxi...

Correlating EGFR Expression with Receptor-Binding Properties and Internalization of 64Cu-DOTA-Cetuxi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4277815

Correlating EGFR Expression with Receptor-Binding Properties and Internalization of 64Cu-DOTA-Cetuximab in 5 Cervical Cancer Cell Lines

About this item

Full title

Correlating EGFR Expression with Receptor-Binding Properties and Internalization of 64Cu-DOTA-Cetuximab in 5 Cervical Cancer Cell Lines

Publisher

United States: Soc Nuclear Med

Journal title

The Journal of nuclear medicine (1978), 2008-09, Vol.49 (9), p.1472-1479

Language

English

Formats

Publication information

Publisher

United States: Soc Nuclear Med

More information

Scope and Contents

Contents

The anti-epidermal growth factor receptor (anti-EGFR) antibody cetuximab is clinically approved for the treatment of EGFR-expressing metastatic colorectal cancer and advanced head and neck cancer. Overexpression of EGFR has also been found in more than 70% of carcinomas of the cervix. The overall goal of this study was to determine whether (64)Cu-1...

Alternative Titles

Full title

Correlating EGFR Expression with Receptor-Binding Properties and Internalization of 64Cu-DOTA-Cetuximab in 5 Cervical Cancer Cell Lines

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4277815

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4277815

Other Identifiers

ISSN

0161-5505

E-ISSN

1535-5667

DOI

10.2967/jnumed.108.052316

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