Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer’s disease early phenot...
Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer’s disease early phenotypes
About this item
Full title
Author / Creator
Marquer, Catherine , Laine, Jeanne , Dauphinot, Luce , Hanbouch, Linda , Lemercier-Neuillet, Camille , Pierrot, Nathalie , Bossers, Koen , Le, Mickael , Corlier, Fabian , Benstaali, Caroline , Saudou, Frédéric , Thinakaran, Gopal , Cartier, Nathalie , Octave, Jean-Noël , Duyckaerts, Charles and Potier, Marie-Claude
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
It is suspected that excess of brain cholesterol plays a role in Alzheimer's disease (AD). Membrane-associated cholesterol was shown to be increased in the brain of individuals with sporadic AD and to correlate with the severity of the disease. We hypothesized that an increase of membrane cholesterol could trigger sporadic AD early phenotypes.
W...
Alternative Titles
Full title
Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer’s disease early phenotypes
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4280040
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4280040
Other Identifiers
ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/1750-1326-9-60
