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Transmembrane channel-like (TMC) genes are required for auditory and vestibular mechanosensation

Transmembrane channel-like (TMC) genes are required for auditory and vestibular mechanosensation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4282624

Transmembrane channel-like (TMC) genes are required for auditory and vestibular mechanosensation

About this item

Full title

Transmembrane channel-like (TMC) genes are required for auditory and vestibular mechanosensation

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Pflügers Archiv, 2015-01, Vol.467 (1), p.85-94

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Mutations of the transmembrane channel-like 1 (
TMC1
) gene can cause dominant and recessive forms of deafness in humans and mice.
TMC1
is one of eight mammalian
TMC
genes of unknown function. The multi-pass transmembrane topologic structure of the proteins they encode suggests roles as a receptor, transporter, channel, or pump.

Alternative Titles

Full title

Transmembrane channel-like (TMC) genes are required for auditory and vestibular mechanosensation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4282624

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4282624

Other Identifiers

ISSN

0031-6768,1432-2013

E-ISSN

1432-2013

DOI

10.1007/s00424-014-1582-3

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