Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas
Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas
About this item
Full title
Author / Creator
Fack, Fred , Espedal, Heidi , Keunen, Olivier , Golebiewska, Anna , Obad, Nina , Harter, Patrick N. , Mittelbronn, Michel , Bähr, Oliver , Weyerbrock, Astrid , Stuhr, Linda , Miletic, Hrvoje , Sakariassen, Per Ø. , Stieber, Daniel , Rygh, Cecilie B. , Lund-Johansen, Morten , Zheng, Liang , Gottlieb, Eyal , Niclou, Simone P. and Bjerkvig, Rolf
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Anti-angiogenic therapy in glioblastoma (GBM) has unfortunately not led to the anticipated improvement in patient prognosis. We here describe how human GBM adapts to bevacizumab treatment at the metabolic level. By performing
13
C
6
-glucose metabolic flux analysis, we show for the first time that the tumors undergo metabolic re-program...
Alternative Titles
Full title
Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas
Authors, Artists and Contributors
Author / Creator
Espedal, Heidi
Keunen, Olivier
Golebiewska, Anna
Obad, Nina
Harter, Patrick N.
Mittelbronn, Michel
Bähr, Oliver
Weyerbrock, Astrid
Stuhr, Linda
Miletic, Hrvoje
Sakariassen, Per Ø.
Stieber, Daniel
Rygh, Cecilie B.
Lund-Johansen, Morten
Zheng, Liang
Gottlieb, Eyal
Niclou, Simone P.
Bjerkvig, Rolf
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4282692
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4282692
Other Identifiers
ISSN
0001-6322
E-ISSN
1432-0533
DOI
10.1007/s00401-014-1352-5
