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Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders

Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4284804

Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders

About this item

Full title

Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2014-12, Vol.5 (1), p.5585-5585, Article 5585

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Mitochondrial diseases are systemic, prevalent and often fatal; yet treatments remain scarce. Identifying molecular intervention points that can be therapeutically targeted remains a major challenge, which we confronted via a screening assay we developed. Using yeast models of mitochondrial ATP synthase disorders, we screened a drug repurposing lib...

Alternative Titles

Full title

Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4284804

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4284804

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms6585

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