Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders
Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders
About this item
Full title
Author / Creator
Aiyar, Raeka S. , Bohnert, Maria , Duvezin-Caubet, Stéphane , Voisset, Cécile , Gagneur, Julien , Fritsch, Emilie S. , Couplan, Elodie , von der Malsburg, Karina , Funaya, Charlotta , Soubigou, Flavie , Courtin, Florence , Suresh, Sundari , Kucharczyk, Roza , Evrard, Justine , Antony, Claude , St.Onge, Robert P. , Blondel, Marc , di Rago, Jean-Paul , van der Laan, Martin and Steinmetz, Lars M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Mitochondrial diseases are systemic, prevalent and often fatal; yet treatments remain scarce. Identifying molecular intervention points that can be therapeutically targeted remains a major challenge, which we confronted via a screening assay we developed. Using yeast models of mitochondrial ATP synthase disorders, we screened a drug repurposing lib...
Alternative Titles
Full title
Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders
Authors, Artists and Contributors
Author / Creator
Bohnert, Maria
Duvezin-Caubet, Stéphane
Voisset, Cécile
Gagneur, Julien
Fritsch, Emilie S.
Couplan, Elodie
von der Malsburg, Karina
Funaya, Charlotta
Soubigou, Flavie
Courtin, Florence
Suresh, Sundari
Kucharczyk, Roza
Evrard, Justine
Antony, Claude
St.Onge, Robert P.
Blondel, Marc
di Rago, Jean-Paul
van der Laan, Martin
Steinmetz, Lars M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4284804
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4284804
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms6585