MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets
MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets
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Author / Creator
Kurioka, A , Ussher, J E , Cosgrove, C , Clough, C , Fergusson, J R , Smith, K , Kang, Y-H , Walker, L J , Hansen, T H , Willberg, C B and Klenerman, P
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Mucosal-associated invariant T (MAIT) cells are an innate-like T-cell population restricted by the non-polymorphic, major histocompatibility complex class I-related protein 1, MR1. MAIT cells are activated by a broad range of bacteria through detection of riboflavin metabolites bound by MR1, but their direct cytolytic capacity upon recognition of c...
Alternative Titles
Full title
MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4288950
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4288950
Other Identifiers
ISSN
1933-0219
E-ISSN
1935-3456
DOI
10.1038/mi.2014.81
