Human breast cancer and lymph node metastases express Gb3 and can be targeted by STxB-vectorized che...
Human breast cancer and lymph node metastases express Gb3 and can be targeted by STxB-vectorized chemotherapeutic compounds
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
The B-subunit of Shiga toxin (STxB) specifically binds to the glycosphingolipid Gb3 that is highly expressed on a number of human tumors and has been shown to target tumor cells in mouse models and ex vivo on primary colon carcinoma specimen.
Using a novel ex vivo STxB labeling (ESL) method we studied Gb3 expression in cytological specimens of p...
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Full title
Human breast cancer and lymph node metastases express Gb3 and can be targeted by STxB-vectorized chemotherapeutic compounds
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4289340
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4289340
Other Identifiers
ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/1471-2407-14-916
