Specific insulin/IGF1 hybrid receptor activation assay reveals IGF1 as a more potent ligand than ins...
Specific insulin/IGF1 hybrid receptor activation assay reveals IGF1 as a more potent ligand than insulin
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
This novel method enables specific measurement of the activation of hybrid receptors formed between the Insulin Receptor (IR) and the Insulin-like Growth Factor 1 Receptor (IGF1R). These hybrid receptors are present in tissues and cell lines expressing both IR and IGF1R. It is therefore challenging to separate the homodimer and hybrid receptor acti...
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Full title
Specific insulin/IGF1 hybrid receptor activation assay reveals IGF1 as a more potent ligand than insulin
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4300458
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4300458
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep07911
