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Enantioselective metabolism of primaquine by human CYP2D6

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Enantioselective metabolism of primaquine by human CYP2D6

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4301821

Enantioselective metabolism of primaquine by human CYP2D6

About this item

Full title

Enantioselective metabolism of primaquine by human CYP2D6

Author / Creator

Fasinu, Pius S , Tekwani, Babu L , Nanayakkara, NP Dhammika , Avula, Bharathi , Herath, HMT Bandara , Wang, Yan-Hong , Adelli, Vijender R , Elsohly, Mahmoud A , Khan, Shabana I , Khan, Ikhlas A , Pybus, Brandon S , Marcsisin, Sean R , Reichard, Gregory A , McChesney, James D and Walker, Larry A

Publisher

England: BioMed Central Ltd

Journal title

Malaria journal, 2014-12, Vol.13 (1), p.507-507, Article 507

Language

English

Formats

Articles

Publication information

Publisher

England: BioMed Central Ltd

Subjects

More information

Scope and Contents

Contents

Primaquine, currently the only approved drug for the treatment and radical cure of Plasmodium vivax malaria, is still used as a racemic mixture. Clinical use of primaquine has been limited due to haemolytic toxicity in individuals with genetic deficiency in glucose-6-phosphate dehydrogenase. Earlier studies have linked its therapeutic effects to CY...

Alternative Titles

Full title

Enantioselective metabolism of primaquine by human CYP2D6

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4301821

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4301821

Other Identifiers

ISSN

1475-2875

E-ISSN

1475-2875

DOI

10.1186/1475-2875-13-507

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