Log in to save to my catalogue

BRAF-mutant melanoma: treatment approaches, resistance mechanisms, and diagnostic strategies

BRAF-mutant melanoma: treatment approaches, resistance mechanisms, and diagnostic strategies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4303458

BRAF-mutant melanoma: treatment approaches, resistance mechanisms, and diagnostic strategies

About this item

Full title

BRAF-mutant melanoma: treatment approaches, resistance mechanisms, and diagnostic strategies

Publisher

New Zealand: Dove Medical Press Limited

Journal title

OncoTargets and therapy, 2015-01, Vol.8, p.157-168

Language

English

Formats

Publication information

Publisher

New Zealand: Dove Medical Press Limited

More information

Scope and Contents

Contents

BRAF inhibitors vemurafenib and dabrafenib achieved improved overall survival over chemotherapy and have been approved for the treatment of BRAF-mutated metastatic melanoma. More recently, the combination of BRAF inhibitor dabrafenib with MEK inhibitor trametinib has shown improved progression-free survival, compared to dabrafenib monotherapy, in a...

Alternative Titles

Full title

BRAF-mutant melanoma: treatment approaches, resistance mechanisms, and diagnostic strategies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4303458

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4303458

Other Identifiers

ISSN

1178-6930

E-ISSN

1178-6930

DOI

10.2147/OTT.S39096

How to access this item