Structure and inhibition of EV-D68, a virus that causes respiratory illness in children
Structure and inhibition of EV-D68, a virus that causes respiratory illness in children
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United States: American Association for the Advancement of Science
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English
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United States: American Association for the Advancement of Science
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Contents
Enterovirus D68 (EV-D68) is a member of Picornaviridae and is a causative agent of recent outbreaks of respiratory illness in children in the United States. We report here the crystal structures of EV-D68 and its complex with pleconaril, a capsid-binding compound that had been developed as an anti-rhinovirus drug. The hydrophobic drug-binding pocke...
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Full title
Structure and inhibition of EV-D68, a virus that causes respiratory illness in children
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4307789
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4307789
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ISSN
0036-8075,1095-9203
E-ISSN
1095-9203
DOI
10.1126/science.1261962
