Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases
Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases
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Author / Creator
Publisher
Boston: Springer US
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Language
English
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Publisher
Boston: Springer US
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Scope and Contents
Contents
The development of in vitro amplification systems allows detecting femtomolar amounts of prion protein scrapie (PrP
Sc
) in human cerebrospinal fluid (CSF). We performed a CSF study to determine the effects of prion disease type, codon 129 genotype, PrP
Sc
type, and other disease-related factors on the real-time quaking-induced conversi...
Alternative Titles
Full title
Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4309904
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4309904
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ISSN
0893-7648
E-ISSN
1559-1182
DOI
10.1007/s12035-014-8709-6