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Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases

Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4309904

Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases

About this item

Full title

Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases

Publisher

Boston: Springer US

Journal title

Molecular neurobiology, 2015-02, Vol.51 (1), p.396-405

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

The development of in vitro amplification systems allows detecting femtomolar amounts of prion protein scrapie (PrP
Sc
) in human cerebrospinal fluid (CSF). We performed a CSF study to determine the effects of prion disease type, codon 129 genotype, PrP
Sc
type, and other disease-related factors on the real-time quaking-induced conversi...

Alternative Titles

Full title

Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4309904

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4309904

Other Identifiers

ISSN

0893-7648

E-ISSN

1559-1182

DOI

10.1007/s12035-014-8709-6

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