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Comprehensive genomic characterization of head and neck squamous cell carcinomas

Comprehensive genomic characterization of head and neck squamous cell carcinomas

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4311405

Comprehensive genomic characterization of head and neck squamous cell carcinomas

About this item

Full title

Comprehensive genomic characterization of head and neck squamous cell carcinomas

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2015-01, Vol.517 (7536), p.576-582

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The Cancer Genome Atlas profiled 279 head and neck squamous cell carcinomas (HNSCCs) to provide a comprehensive landscape of somatic genomic alterations. Here we show that human-papillomavirus-associated tumours are dominated by helical domain mutations of the oncogene
PIK3CA
, novel alterations involving loss of
TRAF3
, and amplificati...

Alternative Titles

Full title

Comprehensive genomic characterization of head and neck squamous cell carcinomas

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4311405

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4311405

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature14129

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