Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen
Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen
About this item
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Author / Creator
Michaelis, Martin , Agha, Bishr , Rothweiler, Florian , Löschmann, Nadine , Voges, Yvonne , Mittelbronn, Michel , Starzetz, Tatjana , Harter, Patrick N. , Abhari, Behnaz A. , Fulda, Simone , Westermann, Frank , Riecken, Kristoffer , Spek, Silvia , Langer, Klaus , Wiese, Michael , Dirks, Wilhelm G. , Zehner, Richard , Cinatl, Jaroslav , Wass, Mark N. and Cinatl, Jindrich
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Flubendazole was shown to exert anti-leukaemia and anti-myeloma activity through inhibition of microtubule function. Here, flubendazole was tested for its effects on the viability of in total 461 cancer cell lines. Neuroblastoma was identified as highly flubendazole-sensitive cancer entity in a screen of 321 cell lines from 26 cancer entities. Flub...
Alternative Titles
Full title
Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen
Authors, Artists and Contributors
Author / Creator
Agha, Bishr
Rothweiler, Florian
Löschmann, Nadine
Voges, Yvonne
Mittelbronn, Michel
Starzetz, Tatjana
Harter, Patrick N.
Abhari, Behnaz A.
Fulda, Simone
Westermann, Frank
Riecken, Kristoffer
Spek, Silvia
Langer, Klaus
Wiese, Michael
Dirks, Wilhelm G.
Zehner, Richard
Cinatl, Jaroslav
Wass, Mark N.
Cinatl, Jindrich
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4314641
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4314641
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep08202
