Co-overexpression of geraniol-10-hydroxylase and strictosidine synthase improves anti-cancer drug ca...
Co-overexpression of geraniol-10-hydroxylase and strictosidine synthase improves anti-cancer drug camptothecin accumulation in Ophiorrhiza pumila
About this item
Full title
Author / Creator
Cui, Lijie , Ni, Xiaoling , Ji, Qian , Teng, Xiaojuan , Yang, Yanru , Wu, Chao , Zekria, David , Zhang, Dasheng and Kai, Guoyin
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Camptothecin (CPT) belongs to a group of monoterpenoidindole alkaloids (TIAs) and its derivatives such as irinothecan and topothecan have been widely used worldwide for the treatment of cancer, giving rise to rapidly increasing market demands. Genes from
Catharanthus roseus
encoding strictosidine synthase (STR) and geraniol 10-hydroxylase (G1...
Alternative Titles
Full title
Co-overexpression of geraniol-10-hydroxylase and strictosidine synthase improves anti-cancer drug camptothecin accumulation in Ophiorrhiza pumila
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4316170
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4316170
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep08227
