MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4
MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4
About this item
Full title
Author / Creator
Walsh, James T. , Hendrix, Sven , Boato, Francesco , Smirnov, Igor , Zheng, Jingjing , Lukens, John R. , Gadani, Sachin , Hechler, Daniel , Gölz, Greta , Rosenberger, Karen , Kammertöns, Thomas , Vogt, Johannes , Vogelaar, Christina , Siffrin, Volker , Radjavi, Ali , Fernandez-Castaneda, Anthony , Gaultier, Alban , Gold, Ralf , Kanneganti, Thirumala-Devi , Nitsch, Robert , Zipp, Frauke and Kipnis, Jonathan
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
A body of experimental evidence suggests that T cells mediate neuroprotection following CNS injury; however, the antigen specificity of these T cells and how they mediate neuroprotection are unknown. Here, we have provided evidence that T cell-mediated neuroprotection after CNS injury can occur independently of major histocompatibility class II (MH...
Alternative Titles
Full title
MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4
Authors, Artists and Contributors
Author / Creator
Hendrix, Sven
Boato, Francesco
Smirnov, Igor
Zheng, Jingjing
Lukens, John R.
Gadani, Sachin
Hechler, Daniel
Gölz, Greta
Rosenberger, Karen
Kammertöns, Thomas
Vogt, Johannes
Vogelaar, Christina
Siffrin, Volker
Radjavi, Ali
Fernandez-Castaneda, Anthony
Gaultier, Alban
Gold, Ralf
Kanneganti, Thirumala-Devi
Nitsch, Robert
Zipp, Frauke
Kipnis, Jonathan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4319416
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4319416
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI76210
