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The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis

The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4319429

The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis

About this item

Full title

The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2015-02, Vol.125 (2), p.539-550

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

In contrast to microbially triggered inflammation, mechanisms promoting sterile inflammation remain poorly understood. Damage-associated molecular patterns (DAMPs) are considered key inducers of sterile inflammation following cell death, but the relative contribution of specific DAMPs, including high-mobility group box 1 (HMGB1), is ill defined. Du...

Alternative Titles

Full title

The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4319429

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4319429

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI76887

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