Activation of β-catenin signalling by TFF1 loss promotes cell proliferation and gastric tumorigenesi...
Activation of β-catenin signalling by TFF1 loss promotes cell proliferation and gastric tumorigenesis
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Publisher
England
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Language
English
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England
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ObjectiveIn this study, we investigated the role of Trefoil factor 1 (TFF1) in regulating cell proliferation and tumour development through β-catenin signalling using in vivo and in vitro models of gastric tumorigenesis.DesignTff1-knockout (Tff1-KO) mice, immunohistochemistry, luciferase reporter, qRT-PCR, immunoblot, and phosphatase assays were us...
Alternative Titles
Full title
Activation of β-catenin signalling by TFF1 loss promotes cell proliferation and gastric tumorigenesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4320984
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4320984
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2014-307191
