GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy
GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Autophagy is a common physiological function in all eukaryotes. The process is induced by depletion of nutrients including amino acids. GADD34 is expressed following DNA damage, ER stresses and amino acid deprivation. Here, we investigated the effects of GADD34 on autophagy and cell activation in macrophages. The deprivation of tyrosine and cystein...
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Full title
GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4321179
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4321179
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep08327
