Cytotoxic effect of lapatinib is restricted to human papillomavirus-positive head and neck squamous...
Cytotoxic effect of lapatinib is restricted to human papillomavirus-positive head and neck squamous cell carcinoma cell lines
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New Zealand: Dove Medical Press Limited
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Language
English
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Publisher
New Zealand: Dove Medical Press Limited
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Contents
Lapatinib is a dual epidermal growth factor receptor (EGFR) and HER2 inhibitor. Overexpression of these receptors is frequently observed in head and neck squamous cell carcinoma (HNSCC). As growing proportion of HNSCC is characterized by human papillomavirus (HPV) infection, we aimed at evaluating the efficacy of lapatinib as function of HPV status...
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Full title
Cytotoxic effect of lapatinib is restricted to human papillomavirus-positive head and neck squamous cell carcinoma cell lines
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4322874
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4322874
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ISSN
1178-6930
E-ISSN
1178-6930
DOI
10.2147/OTT.S68235