The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell...
The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell lines
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In epithelial cells, miRNA-199a-5p/-3p and Brm, a catalytic subunit of the SWI/SNF complex were previously shown to form a double-negative feedback loop through EGR1, by which human cancer cell lines tend to fall into either of the steady states, types 1 [miR-199a(−)/Brm(+)/EGR1(−)] and 2 [miR-199a(+)/Brm (−)/EGR1(+)]. We show here, that type 2 cel...
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Full title
The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell lines
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4325331
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4325331
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep08428
