Structural basis for PPARγ transactivation by endocrine-disrupting organotin compounds
Structural basis for PPARγ transactivation by endocrine-disrupting organotin compounds
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Organotin compounds such as triphenyltin (TPT) and tributyltin (TBT) act as endocrine disruptors through the peroxisome proliferator–activated receptor γ (PPARγ) signaling pathway. We recently found that TPT is a particularly strong agonist of PPARγ. To elucidate the mechanism underlying organotin-dependent PPARγ activation, we here analyzed the in...
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Full title
Structural basis for PPARγ transactivation by endocrine-disrupting organotin compounds
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4330522
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4330522
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep08520
