MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel res...
MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Development of multidrug resistance (MDR) is an almost universal phenomenon in patients with ovarian cancer and this severely limits the ultimate success of chemotherapy in the clinic. Overexpression of the
MDR1
gene and corresponding P-glycoprotein (Pgp) is one of the best known MDR mechanisms.
MDR1
siRNA based strategies were proposed...
Alternative Titles
Full title
MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4330541
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4330541
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep08509
