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Affinity purification–mass spectrometry and network analysis to understand protein-protein interacti...

Affinity purification–mass spectrometry and network analysis to understand protein-protein interacti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4332878

Affinity purification–mass spectrometry and network analysis to understand protein-protein interactions

About this item

Full title

Affinity purification–mass spectrometry and network analysis to understand protein-protein interactions

Publisher

London: Nature Publishing Group UK

Journal title

Nature protocols, 2014-11, Vol.9 (11), p.2539-2554

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

From proteomics to networks, this protocol covers the processing, analysis and interpretation of AP-MS data. Sample data are pre-processed and scored using a variety of methods, and they are then imported into Cytoscape for network analysis and visualization.
By determining protein-protein interactions in normal, diseased and infected cells, we...

Alternative Titles

Full title

Affinity purification–mass spectrometry and network analysis to understand protein-protein interactions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4332878

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4332878

Other Identifiers

ISSN

1754-2189

E-ISSN

1750-2799

DOI

10.1038/nprot.2014.164

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