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Hypo Adenosine-to-Inosine miR-455-5p Editing Promotes Melanoma Growth and Metastasis

Hypo Adenosine-to-Inosine miR-455-5p Editing Promotes Melanoma Growth and Metastasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4344852

Hypo Adenosine-to-Inosine miR-455-5p Editing Promotes Melanoma Growth and Metastasis

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Scope and Contents

Contents

Although recent studies have shown that adenosine-to-inosine (A-to-I) RNA editing occurs in microRNAs, its effects on tumor growth and metastasis are not well understood. We present evidence of CREB-mediated low expression of ADAR1 in metastatic melanoma cell lines and tumor specimens. Re-expression of ADAR1 resulted in the suppression of melanoma...

Alternative Titles

Full title

Hypo Adenosine-to-Inosine miR-455-5p Editing Promotes Melanoma Growth and Metastasis

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Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4344852

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4344852

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/ncb3110

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