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Huntingtin functions as a scaffold for selective macroautophagy

Huntingtin functions as a scaffold for selective macroautophagy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4344873

Huntingtin functions as a scaffold for selective macroautophagy

About this item

Full title

Huntingtin functions as a scaffold for selective macroautophagy

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2015-03, Vol.17 (3), p.262-275

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Selective macroautophagy is an important protective mechanism against diverse cellular stresses. In contrast to the well-characterized starvation-induced autophagy, the regulation of selective autophagy is largely unknown. Here, we demonstrate that Huntingtin, the Huntington disease gene product, functions as a scaffold protein for selective macroa...

Alternative Titles

Full title

Huntingtin functions as a scaffold for selective macroautophagy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4344873

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4344873

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/ncb3101

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