The interaction of escitalopram and R-citalopram at the human serotonin transporter investigated in...
The interaction of escitalopram and R-citalopram at the human serotonin transporter investigated in the mouse
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Rationale
Escitalopram appears to be a superior antidepressant to racemic citalopram. It has been hypothesized that binding of R-citalopram to the serotonin transporter (SERT) antagonizes escitalopram binding to and inhibition of the SERT, thereby curtailing the elevation of extracellular 5-hydroxytryptamine (5-HT
Ext
), and hence antidepr...
Alternative Titles
Full title
The interaction of escitalopram and R-citalopram at the human serotonin transporter investigated in the mouse
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4346315
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4346315
Other Identifiers
ISSN
0033-3158
E-ISSN
1432-2072
DOI
10.1007/s00213-014-3595-1
