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A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface p...

A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface p...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4346626

A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins

About this item

Full title

A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2015-02, Vol.6 (1), p.6341-6341, Article 6341

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Dengue virus (DENV) infects ~400 million people annually. There is no licensed vaccine or therapeutic drug. Only a small fraction of the total DENV-specific antibodies in a naturally occurring dengue infection consists of highly neutralizing antibodies. Here we show that the DENV-specific human monoclonal antibody 5J7 is exceptionally potent, neutr...

Alternative Titles

Full title

A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4346626

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4346626

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms7341

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