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TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translation

TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4348975

TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translation

About this item

Full title

TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translation

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2014-12, Vol.124 (12), p.5424-5436

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The bile acid-responsive G protein-coupled receptor TGR5 is involved in several metabolic processes, and recent studies suggest that TGR5 activation may promote pathways that are protective against diet-induced diabetes. Here, we investigated the role of macrophage-specific TGR5 signaling in protecting adipose tissue from inflammation and associate...

Alternative Titles

Full title

TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4348975

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4348975

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI76289

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