Glucocorticoids mediate induction of microRNA-708 to suppress ovarian cancer metastasis through targ...
Glucocorticoids mediate induction of microRNA-708 to suppress ovarian cancer metastasis through targeting Rap1B
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Glucocorticoids are widely used in conjunction with chemotherapy for ovarian cancer to prevent hypersensitivity reactions. Here we reveal a novel role for glucocorticoids in the inhibition of ovarian cancer metastasis. Glucocorticoid treatments induce the expression of miR-708, leading to the suppression of Rap1B, which result in the reduction of i...
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Glucocorticoids mediate induction of microRNA-708 to suppress ovarian cancer metastasis through targeting Rap1B
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4354140
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4354140
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms6917