Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged F...
Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice
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Author / Creator
Zhou, Linkang , Park, Shi-Young , Xu, Li , Xia, Xiayu , Ye, Jing , Su, Lu , Jeong, Kyeong-Hoon , Hur, Jang Ho , Oh, Hyunhee , Tamori, Yoshikazu , Zingaretti, Cristina M. , Cinti, Saverio , Argente, Jesús , Yu, Miao , Wu, Lizhen , Ju, Shenghong , Guan, Feifei , Yang, Hongyuan , Choi, Cheol Soo , Savage, David B. and Li, Peng
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Fsp27 is a lipid droplet-associated protein almost exclusively expressed in adipocytes where it facilitates unilocular lipid droplet formation. In mice,
Fsp27
deficiency is associated with increased basal lipolysis, ‘browning’ of white fat and a healthy metabolic profile, whereas a patient with congenital CIDEC deficiency manifested an advers...
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Full title
Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4354252
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4354252
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms6949
