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Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture...

Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4355375

Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice

About this item

Full title

Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice

Publisher

England: BioMed Central Ltd

Journal title

Arthritis research & therapy, 2015-02, Vol.17 (1), p.30-30, Article 30

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Previous studies in animal models of osteoarthritis suggest that alendronate (ALN) has antiresorptive and chondroprotective effects, and can reduce osteophyte formation. However, these studies used non-physiologic injury methods, and did not investigate early time points during which bone is rapidly remodeled prior to cartilage degeneration. The cu...

Alternative Titles

Full title

Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4355375

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4355375

Other Identifiers

ISSN

1478-6354

E-ISSN

1478-6362,1478-6354

DOI

10.1186/s13075-015-0546-0

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