Natural history and therapy of TTR-cardiac amyloidosis: emerging disease-modifying therapies from or...
Natural history and therapy of TTR-cardiac amyloidosis: emerging disease-modifying therapies from organ transplantation to stabilizer and silencer drugs
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Publisher
Boston: Springer US
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Language
English
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Publisher
Boston: Springer US
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Contents
Transthyretin-cardiac amyloidoses (ATTR-CA) are an underdiagnosed but increasingly recognized cause of heart failure. Extracellular deposition of fibrillary proteins into tissues due to a variety of inherited transthyretin mutations in ATTRm or due to advanced age in ATTRwt eventually leads to organ failure. In the heart, amyloid deposition causes...
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Full title
Natural history and therapy of TTR-cardiac amyloidosis: emerging disease-modifying therapies from organ transplantation to stabilizer and silencer drugs
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4361302
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4361302
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ISSN
1382-4147
E-ISSN
1573-7322
DOI
10.1007/s10741-014-9462-7