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The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites wit...

The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites wit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4361843

The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites with anionic lipids

About this item

Full title

The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites with anionic lipids

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2015-03, Vol.5 (1), p.9198, Article 9198

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Receptor tyrosine kinases (RTKs) play a critical role in diverse cellular processes and their activity is regulated by lipids in the surrounding membrane, including PIP
2
(phosphatidylinositol-4,5-bisphosphate) in the inner leaflet and GM3 (monosialodihexosylganglioside) in the outer leaflet. However, the precise details of the interactions a...

Alternative Titles

Full title

The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites with anionic lipids

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4361843

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4361843

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep09198

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