MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis
MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis
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United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Accumulation of IL-17-producing Th17 cells is associated with the development of multiple autoimmune diseases; however, the contribution of microRNA (miRNA) pathways to the intrinsic control of Th17 development remains unclear. Here, we demonstrated that miR-21 expression is elevated in Th17 cells and that mice lacking miR-21 have a defect in Th17...
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Full title
MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4362225
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4362225
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ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI74347
