Therapeutic Efficacy and Macrofilaricidal Activity of Doxycycline for the Treatment of River Blindne...
Therapeutic Efficacy and Macrofilaricidal Activity of Doxycycline for the Treatment of River Blindness
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Publisher
United States: Oxford University Press
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Language
English
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Publisher
United States: Oxford University Press
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Background. Onchocerca volvulus and lymphatic filariae, causing river blindness and elephantiasis, depend on endosymbiotic Wolbachia bacteria for growth, development, fertility, and survival. Clinical trials have shown that doxycycline treatment eliminates Wolbachia, causing long-term sterilization of adult female filariae and effecting potent macr...
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Full title
Therapeutic Efficacy and Macrofilaricidal Activity of Doxycycline for the Treatment of River Blindness
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4370165
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4370165
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ISSN
1058-4838
E-ISSN
1537-6591
DOI
10.1093/cid/ciu1152
