Malibatol A regulates microglia M1/M2 polarization in experimental stroke in a PPARγ-dependent manne...
Malibatol A regulates microglia M1/M2 polarization in experimental stroke in a PPARγ-dependent manner
About this item
Full title
Author / Creator
Pan, Jie , Jin, Jia-li , Ge, Hui-ming , Yin, Kai-lin , Chen, Xiang , Han, Li-juan , Chen, Yan , Qian, Lai , Li, Xiao-xi and Xu, Yun
Publisher
England: BioMed Central
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central
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Scope and Contents
Contents
Activation of microglia plays a crucial role in immune and inflammatory processes after ischemic stroke. Microglia is reported with two opposing activated phenotypes, namely, classic phenotype (M1) and the alternative phenotype (M2). Inhibiting M1 while stimulating M2 has been suggested as a potential therapeutic approach in the treatment of stroke...
Alternative Titles
Full title
Malibatol A regulates microglia M1/M2 polarization in experimental stroke in a PPARγ-dependent manner
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4378556
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4378556
Other Identifiers
ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-015-0270-3
